Silymarin and diabetic nephropathy
نویسندگان
چکیده
Nephropathy is one of the most important complications of diabetes mellitus and drug induced toxicity. Nephrotoxicity is mostly related to oxidative stress and nowadays much attention has been made towards the possible kidney protective properties of medicinal plants. Studies revealed, silymarin is useful for diabetic nephropathy. The combination of metformin, silymarin and renin-angiotensin system inhibitors or angiotensin receptor blockers may have additive kidney protective property to prevent or slowing the progression of diabetic nephropathy.
منابع مشابه
Effect of silymarin on streptozotocin-nicotinamide-induced type 2 diabetic nephropathy in rats.
INTRODUCTION Diabetic nephropathy is the major cause of end-stage renal disease worldwide. Silymarin is a flavonoid mixture obtained from Silybum marianum. Various preclinical and clinical studies have revealed that it has antidiabetic activity. The objective of this study was to evaluate the effect of silymarin on type 2 diabetic nephropathy in rats. MATERIALS AND METHODS Non-insulin-depende...
متن کاملBeyond the liver protective efficacy of silymarin; bright renoprotective effect on diabetic kidney disease
Diabetic nephropathy is one of the most important complications of diabetes mellitus (1). Recently much attention has been directed toward the use of silymarin in diabetic nephropathy (2). Silymarin possesses antioxidant and antiproteinuric effects in humans and in animal models (2,3). Silymarin seems to have two different effects in diabetic patients (2,3). Firstly control of blood sugar and s...
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2012